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目的:调查护师主导的营养和运动联合干预对超重成人的体重、人体成分和肥胖发生率的影响。方法:连续收集来自健康体检中心符合纳入标准并获知情同意的超重成人103例,随机分为研究组(n=51)和对照组(n=52),分别接受为期6个月护师主导强化营养运动联合干预(研究组)或常规营养咨询(对照组)。测定并比较两组干预前后体重指数、非脂肪组织、体脂率、腰臀围比、肥胖和腹型肥胖发生率。结果:干预6个月后,研究组平均能量摄入量降低[(92.4±27.2)kJ/(kg·d)比(143.4±23.8)kJ/(kg·d),P=0.035],而规律运动比例增高(41.2%比19.2%,P=0.015)。与对照组比较,研究组体重指数[(22.9±2.1)kg/mn 2比(27.3±2.3)kg/mn 2,P=0.045)]、体脂率(25.2%±5.5%比32.5%±6.3%,P=0.035)、腰臀围比[(0.88±0.47)比(0.93±0.58),P=0.040]、肥胖(7.8%比23.1%,P=0.033)和腹型肥胖(7.8%比25.0%,P=0.019)发生率均显著降低。n 结论:护师主导营养和运动联合干预可改善超重成人体重和人体组成状况,并降低肥胖风险。“,”Objective:To investigate the effect of nurse-led intervention with nutrition and physical exercise combined on body mass index, body composition and incidence of obesity in adults with overweight.Methods:A total of 103 adults with overweight who met enroll criteria and signed informed consent were consecutively enrolled from health examination center, and were randomized into study (n n=51) and control groups(n n=52) to receive a 6-month nurse-led intensive nutrition combined physical exercise intervention (study group) or routine nutrition consultation (control group) respectively. Body mass index (BMI), fat-free mass (FFM), body fat rate (BF%), waist-to-hip ratio (WHR), incidence of obesity and abdominal obesity were measured and compared between the two groups pre- and after the intervention.n Results:After 6-month intervention, the average energy intake decreased [(92.4±27.2) n vs(143.4±23.8)kJ/(kg·d), n P=0.035], while the percent of regular physical exercise increased (41.2% n vs 19.2%, n P=0.015) in study group. Compared to control group, BMI[(22.9±2.1)n vs (27.3±2.3)kg/mn 2, n P=0.045], body fat rate(25.2%±5.5% n vs 32.5%±6.3%, n P=0.035), WHR(0.88±0.47 n vs 0.93±0.58, n P=0.040), incidence of obesity (7.8% n vs 23.1%, n P=0.033) and abdominal obesity (7.8% n vs 25.0%, n P=0.019) decreased significantly in study group.n Conclusion:Nurse-led nutrition combined physical exercise intervention can improve body weight and body composition, as well as decrease the risk of obesity.