骨髓间充质干细胞(MSCs)主要存在于骨髓中,在脐血、外周血、脂肪、皮肤等多种组织中也相继分离出MSCs。MSCs具有多向分化的能力,在一定条件下可分化为各种不同来源的细胞。目前,MSCs的分离培养、诱导分化及鉴定体系已趋成熟,其在临床应用的前景广阔。血管内皮细胞(VECs)来源于中胚层,因此MSCs具有分化为VECs的可能性。 Bone marrow mesenchymal stem cells (MSCs) are mainly found in the bone marrow, and MSCs are also isolated from many tissues such as cord blood, peripheral blood, fat and skin. MSCs have the ability of multi-directional differentiation, under certain conditions can differentiate into a variety of different sources of cells. At present, the isolation, culture, differentiation and identification system of MSCs have matured, and have a bright future in clinical application. Vascular endothelial cells (VECs) are derived from the mesoderm, so MSCs have the potential to differentiate into VECs.