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为探讨复发性阿弗它溃疡（ＲＡＵ）与单纯疱疹病毒（ＨＳＶ）的关系，作者采用聚合酶链反应（ＰＣＲ）技术检测５０例ＲＡＵ患者的溃疡区、非溃疡区和原溃疡愈后粘膜三个部位的ＨＳＶ－ＤＮＡ。结果，ＨＳＶ－ＤＮＡ的检出率是：溃疡区２４％（１２／５０），非溃疡区１０％（５／５０），原溃疡愈后粘膜６％（３／５０）；对照组６．６６％（２／３０）。溃疡区与对照组之间的ＨＳＶ－ＤＡＮ检出率有显著性差异。提示部分ＲＡＵ患者与ＨＳＶ感染有关，ＨＳＶ可能参与ＲＡＵ损害形成过程
To investigate the relationship between recurrent aphthous ulcer (RAU) and herpes simplex virus (HSV), the authors used polymerase chain reaction (PCR) to detect 50 cases of RAU patients with ulcer, non-ulcer and ulcer healing mucosal three HSV-DNA at each site. Results: The detection rate of HSV-DNA was 24% (12/50) in ulcer area, 10% (5/50) in non-ulcer area and 6% (3/50) in ulcer healing area. The control group % (2/30). There was a significant difference in the detection rate of HSV-DAN between the ulcer area and the control group. It is suggested that some RAU patients are associated with HSV infection, HSV may be involved in the process of RAU damage