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目的 :呼气氢气试验测定胃泌酸功能的临床应用及意义。方法 :对 89例胃、十二指肠疾病患者口服金属镁胶囊 ,通过电化学微量氢气分析仪收集呼气氢 ,测定胃泌酸功能并与常规胃液分析方法进行对照。结果 :89例患者的胃酸排出量与产氢量呈正相关 (r =0 .793 5 ,P <0 .0 1) ;十二指肠球部溃疡的产氢量明显高于非球部溃疡患者 ,其中幽门螺杆菌阳性者的产氢量明显高于幽门螺杆菌阴性者 (P <0 .0 0 1) ,萎缩性胃炎患者的产氢量明显低于非萎缩性胃炎患者 ;口服金属镁前后的血、尿、粪常规及肝、肾功能检查无变化。结论 :口服金属镁胶囊呼气氢试验是一种测定胃泌酸功能的可靠方法。
Objective: The clinical application of breath hydrogen test in the determination of gastrin function and its significance. Methods: Eighty-nine patients with gastric and duodenal diseases were orally administered with magnesium metal capsules. The exhaled hydrogen was collected by electrochemical micro-hydrogen analyzer. Gastrin function was measured and compared with conventional gastric juice analysis. Results: There was a positive correlation between gastric acid secretion and hydrogen production in 89 patients (r = 0.793 5, P <0.01). Hydrogen production in duodenal ulcer was significantly higher than that in non-ulcer patients , Of which Helicobacter pylori positive hydrogen production was significantly higher than Helicobacter pylori negative (P <0.01), atrophic gastritis patients with hydrogen production was significantly lower than non-atrophic gastritis patients; oral administration of magnesium before and after The blood, urine, fecal routine and liver, kidney function check no change. Conclusion: Oral metallic magnesium capsule expiratory hydrogen test is a reliable method of determining gastric acid secretion.