论文部分内容阅读
用荧光分光光度法测定硒化卡拉胶（硒宝康）胶囊在兔体内的生物利用度。结 果：血Ｓｅ达峰时间（ｔｍａｘ）５．０５ ｈ，最大峰浓度（Ｃｍａｘ）１１５．２９μｇ／Ｌ，药时曲线下面积（ＡＵＣ０→２４） １６４８．７９μｇ·Ｌ－１·ｈ。结论：硒宝康胶囊的生物利用度较亚硒酸钠胶囊大，两种含硒药物间有显 著差异（Ｐ＜０．０５），前者维持时间也较长，是一优于亚硒酸钠胶囊的补硒制剂。
Determination of bioavailability of selenated carrageenan capsule in rabbits by fluorescence spectrophotometry. Results: The blood peak time (t max) was 5.05 h, the maximum peak concentration (Cmax) was 115.29 μg / L, and the area under the curve of medicine time (AUC0 → 24) was 1648.79 μg · L-1 · h. Conclusion: The bioavailability of selenium Baokang capsule is larger than that of sodium selenite capsules, the difference between the two selenium drugs is significant (P <0.05), and the former is longer, which is better than sodium selenite Capsule selenium preparation.