乳腺癌容易发生骨内转移形成亲骨性肿瘤，但乳腺癌细胞因破坏骨基质的产生和释放溶解酶及胶原酶直接吸收骨组织，所以多为溶骨性转移。本例患者为多发成骨硬化转移，临床罕见。患者，女，４７岁。于１９９０年１０月发现左侧乳房肿物，约１ｃｍ×０．８ｃｍ×０．５ｃｍ大小，? Breast cancer is prone to intraosseous metastasis to form osteophilic tumors, but breast cancer cells are mostly osteolytic because they destroy the production of bone matrix and release lytic enzymes and collagenase and directly absorb bone tissue. In this case, there were multiple osteoblastic sclerosis metastases, which were rare in clinical practice. Patient, female, 47 years old. In October 1990, the left breast mass was found to be about 1cm x 0.8cm x 0.5cm in size.