目的　观察小儿哮喘缓解期口服小剂量氨茶碱的疗效。方法　在哮喘缓解期采用长期口服小剂量氨茶碱治疗儿童轻、中度哮喘 32例。氨茶碱按每次 3mg/kg ,每 8h 1次 ,疗程 1年。 结果　经 1年治疗显示患儿的发作次数减少 ,发作持续时间缩短和第一秒用力呼气量 (FEV1)增加 (P <0 0 1)。一年中氨茶碱血药浓度在 5～7 5mg/L。 结论　本疗法效果满意 ,未见副作用 Objective To observe the efficacy of oral low dose aminophylline in pediatric asthma remission period. Methods Long-term low-dose oral aminophylline was used to treat 32 mild and moderate asthma children during asthma remission. Aminophylline by 3mg / kg every 8h 1, course of treatment for 1 year. Results One year of treatment showed fewer episodes, shorter duration of episodes, and increased forced expiratory volume in one second (FEV1) (P <0.01). Aminophylline plasma concentration in the year 5 ~ 7 5mg / L. Conclusion The effect of this therapy is satisfactory, no side effects