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目的：了解药品不良反应（ ADR）发生的特点和规律。方法对我院2012年上报的117例ADR报告回顾性统计、分析。结果117例ADR中，10岁以下患者最多，占33.33％；引发ADR的给药途径以静脉滴注给药为主，占77.78％；由抗微生物药引发的ADR最多，占34.19％；由维生素类药物引发的严重ADR最多，占36.36％；ADR累及器官或系统以皮肤及其附件损害最常见，占36.05％。结论医院应重视ADR的监测工作，尤其是对重点人群和重点药品，以减少ADR的发生，保障患者用药安全。“,”Objective To investigate the characteristics and regulations of adverse drug reaction ( ADR) in our hospital.Methods 117 ADR in our hospital in 2012 were analyzed statistically.Results Of total 117 cases,most were senile patients aged below 10 years old,account for 33.33%;most of ADR were induced by intravenous dripping ,accounting for 77.78%;most of ADR were in-duced by antimicrobial drugs ,accounting for 34.19%;most of severe ADR were induced by vitamins ,account for 36.36%;the most common clinical manifestations were the damage of skin and appendants ,accounting for 36.05%.Conclusion Importance should be attached to ADR report and monitoring ,especially focus groups and key drug ,to avoid the incidence of ADR to ensure the safety of drug use in patiens.