唐氏综合征(先天愚型)系21三体性染色体异常〈21Trisomie〉,其在眼科的常见表现是睑裂狭小,内眦赘皮、从内下到外上的眼裂倾斜、斜视、屈光不正与虹膜 Brushfield 氏斑,先天性白内障少见。角膜的变化以急性园锥角膜为主。作者在他的1116例先天性愚型病人中,发现有10例(0.9%)急性园锥角膜。所有病例均有眼睛突然发红与疼痛、进行性视力减退、明显的角膜混浊、以及流泪、羞明与限睑痉挛的病史。裂隙灯下角膜中央混浊,呈园 Down Syndrome (Down’s Syndrome) Department of trisomy 21 chromosomal abnormalities <21Trisomie>, its common manifestations in ophthalmology are palpebral fissure narrow, epicanthus, from the inside to the outside of the eyelid tilt, strabismus, flexor Irregular light and iris Brushfield’s spot, rare congenital cataract. Corneal changes to acute keratoconus based. In 1116 cases of congenital stupidity, he found 10 cases (0.9%) of acute keratoconus corneas. All cases had sudden redness and pain in the eyes, progressive visual loss, significant corneal opacity, and a history of tearing, shame, and blepharospasm. Slit lamp corneal central cloudy, was Park