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目的观察初治失败肺结核患者采用2H3R3Z3E3/6H3R3E3或3H3R3Z3E3/5H3R3E3化疗方案的治疗效果,探讨肺结核初治失败患者对上述治疗方案的反应。方法为对我院2002-2005年登记在册、转归报表、管理卡中初治失败的106例肺结核患者,采用2H3R3Z3E3/6H3R3E3或3H3R3Z3E3/5H3R3E3化疗方案(初治涂阳方案)进行治疗,其间第2、5、8、12个月各查痰1次,连续2次痰菌阴性为治愈,否则为治疗失败。治疗结束后对结果进行统计学分析,对上述化疗方案的副作用进行分析。结果全部106例患者中治愈84例(79.3%),失败16例(15.1%),死亡6例(5.7%)。结论对初治失败患者采用2H3R3Z3E3/6H3R3E3或3H3R3Z3E3/5H3R3E3初治涂阳化疗方案的治疗有一定疗效。
Objective To observe the therapeutic effect of 2H3R3Z3E3 / 6H3R3E3 or 3H3R3Z3E3 / 5H3R3E3 chemotherapy regimens in patients with newly diagnosed pulmonary tuberculosis failure and to investigate the response to the above treatment regimens in patients with initially failed pulmonary tuberculosis. Method for the registration of our hospital in 2002-2005 registered in the report, the report card management failed initial treatment of 106 cases of pulmonary tuberculosis patients with 2H3R3Z3E3 / 6H3R3E3 or 3H3R3Z3E3 / 5H3R3E3 chemotherapy (initial smear program) for treatment, during which the first 2, 5, 8, 12 months of sputum examination 1, 2 consecutive sputum negative for cure, otherwise the failure of treatment. After the treatment, the results were statistically analyzed, and the side effects of the above chemotherapy regimens were analyzed. Results Of the 106 patients, 84 (79.3%) were cured, 16 (15.1%) failed and 6 (5.7%) died. Conclusion The initial treatment failed patients with 2H3R3Z3E3 / 6H3R3E3 or 3H3R3Z3E3 / 5H3R3E3 initial smear chemotherapy regimen have a certain effect.