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目的 将强化护理管理对尿毒症血液透析患者残余肾功能及生活质量的影响效果进行探讨。方法 采纳2017年1月至2019年1月在我院进行治疗的尿毒症血液透析患者48例，根据患者的入院治疗时间随机分为对照组与观察组各24例，对照组患者在行常规治疗与血液透析的基础上给予普通护理，观察组患者在此基础上给予强化护理管理模式，将两组患者进行干预后的残余肾功能、胆固醇水平、干预前后的SAS焦虑评分、SDS抑郁评分及干预后1个月、3个月后的WHOQOL-BREF 生活质量评分变化进行比较。结果 行干预后，观察组患者的残余肾功“,”Objective To investigate the effect of intensive nursing management on residual renal function and quality of life in hemodialysis patients with uremia. Methods Forty eight cases of uremia hemodialysis were treated in our hospital from January 17 to January 19， and were randomly divided into 24 cases in the control group and 24 in the observation group according to the time of admission. The patients in the control group were in regular treatment. On the basis of hemodialysis， general care was given. The patients in the observation group were given intensive nursing management model on this basis. The residual renal function， cholesterol level， SAS anxiety score before and after intervention， SDS depression score， and WHO QOL-BREF quality of life score changes 1 month and 3 months after intervention were compared between the two groups. Results After intervention， the residual renal function and cholesterol levels of the patients in the observation group were significantly improved. Before intervention， there was no significant difference between the SAS and SDS scores in the two groups (P＞0.05). After intervention，The SAS and SDS scores of the patients in the observation group were significantly reduced， and the WHO QOL-BREF score was higher after 1 month and 3 months of patient intervention in the observation group (P＜0.05). The total satisfaction rate of nursing in the observation group was significantly higher than that in the control group (P＜0.05). Conclusion For uremia patients undergoing hemodialysis treatment， the use of intensive care model can protect the residual renal function to the greatest extent and improve the quality of life.