原发中枢神经系统淋巴瘤(primary central nervous system lymphoma,PCNSL)是一种侵袭性非常高的淋巴瘤,原发于大脑、脊髓、眼及附属器(眼框内)、脑脊膜、颅神经,占所有淋巴瘤的1%,结外淋巴瘤的4%~6%,中枢神经系统肿瘤的3%。病理类型95%以上是弥漫大B细胞淋巴瘤,近年来在免疫功能正常的人群中发病率有增加趋势[1]。原发中枢神经系统淋巴瘤预后较差,自然病程仅数月。我们用自 Primary central nervous system lymphoma (PCNSL) is a very aggressive lymphomas originating in the brain, spinal cord, eyes and appendages (intracranial), meninges, cranial nerves , Accounting for 1% of all lymphomas, 4% to 6% of extranodal lymphoma, and 3% of CNS tumors. More than 95% of the pathological types are diffuse large B-cell lymphoma, and in recent years the incidence has been increasing in people with normal immune function [1]. Primary central nervous system lymphoma prognosis is poor, the natural course of only a few months. We use self