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目的探讨急性脑梗死患者血清IL-6及TNF-α的变化规律。方法选取2009年4月-2012年4月于本院进行治疗的62例急性脑梗死患者为观察组,同期进行体检的62名健康人为对照组,将两组人员的血清IL-6及TNF-α水平和阳性率进行统计及比较。结果观察组血清IL-6及TNF-α含量及阳性率均高于对照,同时重度患者高于轻度与中度患者,而中度患者高于轻度患者,P均<0.05,有显著性差异。结论急性脑梗死患者血清IL-6及TNF-α呈现升高的状态,且对严重程度的了解有一定的临床意义。
Objective To investigate the changes of serum IL-6 and TNF-α in patients with acute cerebral infarction. Methods Sixty-two patients with acute cerebral infarction who were treated in our hospital from April 2009 to April 2012 were selected as the observation group. Sixty-two healthy subjects who underwent physical examination during the same period were selected as the control group. Serum IL-6 and TNF- α levels and positive rate statistics and comparison. Results The serum levels of IL-6 and TNF-α in the observation group were higher than those in the control group, while those in the severe group were higher than those in the mild and moderate groups, while those in the moderate group were higher than those in the mild group difference. Conclusion Serum levels of IL-6 and TNF-α in patients with acute cerebral infarction show an elevated status, and understanding of the severity of the disease has some clinical significance.