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目的:探讨99m锝-甲氧基异丁基异腈(99mTc-methoxy isobutyl isonitrile,Tc-MIBI)评估冠状动脉支架置入术(支架置入术)后损伤区心肌细胞血流灌注状况的价值。方法::40例行支架置入术患者,分别在置入术前、后进行99mTc-MIBI心肌静态显像及其硝酸异山梨酯(ISDN)介入显像,对比分析损伤区心肌细胞血流灌注改善程度。结果:40例患者冠状动脉共有360个节段。术前Tc-MIBI ISDN介入显像异常109个节段(29.2%),显著少于Tc-MIBI静态显像异常的178个节段(49.4%,P<0.01)。支架置入术后ISDN介入显像异常91个(25.3%)节段也显著少于静态显像异常的112个节段(31.1%,P<0.05)。结论:99mTc-MIBI-ISDN介入显像较99mTc-MIBI心肌静态显像更能反映支架置入术后心肌血流灌注情况。
Objective: To investigate the value of 99mTc-methoxy isobutyl isonitrile (99mTc-methoxy isobutyl isonitrile, Tc-MIBI) in assessing the perfusion of myocardial cells after coronary stenting (stent implantation). Methods: Forty patients underwent stent implantation, 99mTc-MIBI myocardial static imaging and isosorbide dinitrate (ISDN) interventional imaging were performed before and after implantation, and the myocardial perfusion Degree of improvement. Results: A total of 360 coronary arteries were obtained in 40 patients. There were 109 segments (29.2%) of preoperative Tc-MIBI ISDN imaging abnormalities, which were significantly less than 178 segments (49.4%, P <0.01) of Tc-MIBI static imaging abnormalities. 91 (25.3%) segments of ISDN imaging were significantly less than 112 segments of static imaging abnormalities (31.1%, P <0.05) after stent implantation. Conclusion: 99mTc-MIBI-ISDN imaging can better reflect myocardial perfusion after stent implantation than 99mTc-MIBI myocardial static imaging.