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为探讨脑血栓形成患者凝血、纤溶功能的演变规律，采用ELISA法监测30例脑血栓形成患者血浆纤维蛋白肽A（FPA）和D－二聚体（DD）在急性期和恢复期的变化，并与20例正常人比较。结果显示：脑血栓形成患者急性期和恢复期血浆FPA、DD浓度均显著高于正常对照组（均P＜0．01），急性期和恢复期比较差异均无显著性（均P＞0．05）。提示：脑血栓形成患者存在着持续时间较长的凝血机能亢进，其在脑血栓形成的发展和复发中可能起重要作用；脑血栓形成患者存在着继发性纤溶功能亢进，可能与机体对血栓形成的应答反应有关。
To investigate the evolution of coagulation and fibrinolytic function in patients with cerebral thrombosis, the changes of plasma fibronectin A (FPA) and D-dimer (DD) in 30 patients with cerebral thrombosis during acute phase and convalescence were monitored by ELISA , And compared with 20 normal subjects. The results showed that the concentration of plasma FPA and DD in patients with cerebral thrombosis at acute and convalescent stage were significantly higher than those in normal control group (all P <0.01). There was no significant difference between acute and convalescent patients (all P> 0). 05). Tip: Patients with cerebral thrombosis have a longer duration of coagulopathy, which may play an important role in the development and recurrence of cerebral thrombosis; patients with cerebral thrombosis secondary to fibrinolytic hyperactivity may be related to the body Thrombosis response to the reaction.