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在食管癌的发生发展过程中VEGF、COX-2起着重要的作用,COX-2可以诱导食管癌的发生,VEGF促进食管肿瘤的生成,其表达的高低与食管癌的生物学行为密切相关。检测其表达量与指导食管癌的临床治疗及预后有重要意义。
VEGF and COX-2 play an important role in the development and progression of esophageal cancer. COX-2 can induce the occurrence of esophageal cancer. VEGF can promote the formation of esophageal cancer. The expression of VEGF and COX-2 are closely related to the biological behavior of esophageal cancer. To detect the expression of esophageal cancer and guide the clinical treatment and prognosis of great significance.