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作者对肾病患者和健康对照组用商陆有丝分裂原(PWM)刺激淋巴细胞进行免疫球蛋白合成的研究。作者发现与微小病变型肾炎,膜性肾小球肾炎,和膜增殖性肾小球肾炎有关的肾病综合征患者,其IgG的合成缺陷。这三类患者在试管中合成IgG以及每组患者的血清IgG的平均水平均比对照组明显低下。微小病变型肾炎患者IgG的生成减少及血清IgG水平下降在康复后,可以完全恢复正常。数据表明,在
The authors studied immunoglobulin synthesis in patients with nephropathy and healthy controls by stimulating lymphocytes with pliocene mitogen (PWM). The authors found defects in the synthesis of IgG in patients with nephrotic syndrome associated with microcytic glomerulonephritis, membranous glomerulonephritis, and membranoproliferative glomerulonephritis. The three groups of patients synthesize IgG in test tubes and the average level of serum IgG in each group is significantly lower than the control group. Minimally-modified nephritis in patients with reduced production of IgG and serum IgG levels decreased after recovery, can be completely returned to normal. The data shows that