国际航行船舶外来医学媒介生物输入风险因素的Meta分析

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目的综合分析外来医学媒介生物通过国际航行船舶输入的风险因素。方法运用Meta分析方法对国内有关外来医学媒介生物输入风险因素的4项研究结果进行了定量综合分析并绘制森林图,累计分析媒介阳性船舶、对照船舶分别为1 206和14 555艘,统计处理主要采用Dersimonian和Laird的随机效应模型。结果对4项研究的Meta分析表明:船龄、到达季节、来源地属传染病疫区、曾检出媒介生物、货物种类为动植物产品或矿石煤炭等5项因素与船舶携带外来媒介生物的可能性呈正关联(综合OR均大于1),其中,曾检出媒介生物、货物种类为动植物产品与船舶携带外来媒介生物有较高的关联度(综合OR均大于4)。结论经过Meta分析筛选出的5项因素是外来医学媒介生物通过国际航行船舶输入的重要风险因素,检验检疫机关应重点针对这些因素加大对国际航行船舶的检疫监管,防止外来媒介生物及其携带的病原体传入我国。 Objective To comprehensively analyze the risk factors imported by foreign medical vector organisms through international voyages. Methods Meta-analysis was used to quantitatively analyze and draw the results of four studies on the risk factors of imported medical organism in China. The total number of media-positive ships and control ships was 1,206 and 14,555, respectively. Adopt Dersimonian and Laird’s random effects model. Results The Meta-analysis of the 4 studies showed that the five factors of age, arrival season, origin of infectious disease, detection of vector organisms, species of animal or plant products or ore and coal, and the possibility of carriers carrying foreign vectors (All ORs were greater than 1). Among them, medium organisms and cargo species were found to have higher association with animals and plants carrying foreign vector organisms (overall OR greater than 4). Conclusion The five factors screened by Meta-analysis are important risk factors for importation of foreign medical vectors by ships of international voyages. The inspection and quarantine authorities should focus on these factors to increase the quarantine and supervision of ships on international voyages and prevent the carriage of foreign vectors and their carriers The pathogen into our country.
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