论文部分内容阅读
An efficient diketene ring-opening synthesis of polyhydroquinoline derivatives using SBA-15 sulfonic acid modified mesoporous substrates a green and reusable catalyst in a single-pot four-component coupling reaction of diketene,alcohol,enamine,and aldehydes is reported.Dihydropyridine derivatives based on neat adduct of diketene,alcohols and aldehydes using SBA-15/SO_3H nanoreactor as catalyst via a four-component reactions are also synthesized.The advantages of the present method include the use of a small amount catalyst,simple procedure with an easy filterable work-up,waste-free,green and direct synthetic method with an excellent yield of products with efficient use of catalyst and a short reaction time.
An efficient diketene ring-opening synthesis of polyhydroquinoline derivatives using SBA-15 sulfonic acid modified mesoporous substrates a green and reusable catalyst in a single-pot four-component coupling reaction of diketene, alcohol, enamine, and aldehydes is reported. Dihydropyridine derivatives based on neat adduct of diketene, alcohols and aldehydes using SBA-15 / SO_3H nanoreactor as catalyst via a four-component reactions are also incorporated. advantages of the present method include the use of a small amount catalyst, simple procedure with an easy filterable work- up, waste-free, green and direct synthetic method with an excellent yield of products with efficient use of catalyst and a short reaction time.