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目的探究盐酸氟西汀在缺血性脑卒中后期康复中的作用。方法选取南阳医学高等专科学校一附院神经内科2013年10月-2015年10月收治的306例缺血性脑卒中患者作为研究对象,分为观察组(168例)和对照组(138例)。对照组给予常规脑卒中后康复理疗,观察组在对照组治疗的基础上,加服盐酸氟西汀分散片。结果(1)观察组的蒙特利尔评价认知表(MoCA)评分及简易智能精神状态检查表(MMSE)评分均明显高于对照组,差异有统计学意义(P<0.05);(2)对照组威斯康星卡片分类检查表(WCST)评分中的应答错误数评分和持续性应答错误数评分高于观察组,观察组WCST评分中的完成分类数评分高于对照组,差异均有统计学意义(P<0.05)。结论盐酸氟西汀分散片对于脑卒中后患者的认知功能和执行功能的恢复具有一定的临床疗效。
Objective To investigate the role of fluoxetine in the rehabilitation of patients with ischemic stroke. Methods A total of 306 ischemic stroke patients admitted to the First Affiliated Hospital of Nanyang Medical College from October 2013 to October 2015 were enrolled in this study. The patients were divided into observation group (168 cases) and control group (138 cases) . The control group was given conventional post-stroke rehabilitation therapy. The observation group was given fluoxetine hydrochloride dispersible tablets on the basis of the control group. Results (1) The scores of MoCA and MMSE in the observation group were significantly higher than those in the control group (P <0.05). (2) In the control group WCST scoring scores in the score of false positives and persistent error scores were higher than those in the observation group, and WCST scores in the observation group were higher than those in the control group (P <0.05). Conclusion Fluoxetine hydrochloride dispersible tablets have certain clinical efficacy for the recovery of cognitive function and executive function in patients after stroke.