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目的比较连续肾脏替代疗法(CRRT)不同治疗时间治疗脓毒症急性肾衰竭的疗效。方法选取桂林医学院附属医院2011年1月—2015年5月收治的脓毒症急性肾衰竭患者44例,并根据其CRRT治疗时间的不同分为短时间组与长时间组,每组22例。治疗前后分别检测记录两组患者的尿素氮、肌酐、心率、急性生理功能和慢性健康状况评分系统(APACHEⅡ)评分、进入多尿期及肌酐恢复正常的时间等指标。记录两组患者死亡、存活、肾功能稳定的人数。结果治疗前后两组患者的尿素氮、肌酐、心率、APACHEⅡ评分、进入多尿期及肌酐恢复正常时间比较,差异无统计学意义(P>0.05);两组患者存活率、肾功能稳定率比较,差异无统计学意义(P>0.05)。结论CRRT短时间与长时间治疗脓毒症急性肾衰竭的疗效相当。
Objective To compare the efficacy of continuous renal replacement therapy (CRRT) at different treatment time in the treatment of acute renal failure with sepsis. Methods Forty-four patients with acute renal failure of sepsis admitted to Affiliated Hospital of Guilin Medical College from January 2011 to May 2015 were divided into short-term group and long-term group according to their CRRT treatment time, with 22 cases in each group . The levels of urea nitrogen, creatinine, heart rate, acute physiology and chronic health assessment score (APACHEⅡ) were recorded and recorded before and after treatment. Two groups of patients were recorded death, survival, renal function and stability of the number. Results Before and after treatment, the levels of urea nitrogen, creatinine, heart rate, APACHEⅡ score, urine polyuria and creatinine return time were not significantly different between the two groups (P> 0.05). The survival rate and the stability rate of renal function were compared between the two groups , The difference was not statistically significant (P> 0.05). Conclusion CRRT is effective in treating acute renal failure with sepsis for a short period of time.