氨苄青霉素(ABPC)在小儿科范围内作为静注、肌注、口服药广泛地使用着。但由于暖气、口腔炎引起疼痛、厌药等原因,口服常有困难。另外,用以注射时,不仅患儿感到痛苦,特别还存在注射次数和肌注发生局部副作用等问题。因此,临床中考虑到使用栓剂,通过肛门直肠内给药这一全身用药的方法。目前在抗生素中,除红霉素外尚无栓剂可用。 Ampicillin (ABPC) is widely used in pediatrics as intravenous, intramuscular and oral medication. However, due to heating, stomatitis caused by pain, fatigue and other reasons, oral often difficult. In addition, for injection, not only children feel pain, in particular, there are injection times and intramuscular injection of local side effects and other issues. Therefore, clinically a suppository is taken into account for the systemic administration via the anorectal route. Currently in antibiotics, there is no suppository available except erythromycin.