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目的:探讨急性冠脉综合征患者血浆中Hcy、h S-CRP和BNP的变化水平以及关系。方法:选取本院于2015年1月~2016年1月间收治的180例冠心病患者,按照病情将患者分为急性冠脉综合征组和稳定型心绞痛组,另外选取80例健康人群作为对照组,比较分析三组患者血浆中Hcy、h S-CRP和BNP的变化水平以及对于急性冠脉综合征预后影响情况。结果:急性冠脉综合征组血浆中的Hcy、h S-CRP和BNP三种水平均显著高于稳定型心绞痛组和对照组;急性冠脉综合征患者的血浆随着Hcy水平增加而升高,与h S-CRP以及BNP水平呈正相关。结论:血浆中的Hcy、h S-CRP和BNP三种水平之间的差异反映出患者冠心病不同疾病表征,根据血液中三种物质的水平高低可以对患者疾病进行判定,同时还可根据血浆中Hcy、h S-CRP和BNP三种水平来评估患者的预后能力。
Objective: To investigate the changes of plasma levels of Hcy, h S-CRP and BNP in patients with acute coronary syndrome. Methods: 180 patients with coronary heart disease admitted from January 2015 to January 2016 in our hospital were divided into two groups: acute coronary syndrome group and stable angina pectoris group. Eighty healthy subjects were selected as control group Group, comparative analysis of three groups of plasma Hcy, h S-CRP and BNP levels and prognosis of acute coronary syndrome. Results: The levels of Hcy, h S-CRP and BNP in plasma of patients with acute coronary syndrome were significantly higher than those of patients with stable angina and control group. The plasma of patients with acute coronary syndrome increased with the increase of Hcy , Positively correlated with h S-CRP and BNP levels. Conclusion: The differences of Hcy, h S-CRP and BNP levels in plasma reflect the characteristics of different diseases in patients with coronary heart disease. According to the level of three substances in the blood, the patients’ diseases can be judged. At the same time, Hcy, h S-CRP and BNP levels to assess the patient’s prognosis.