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目前对发生转移的头颈鳞癌(SCCHN)的研究报道很少,首次采用诱导化疗的患者,局部病灶反应明显,预后较复发患者更好。该文作者对2008年1月-2012年7月收治的SCCHN患者进行回顾分析。采用Kaplan-Meier法计算生存率。结果,在纳入的749例患者中,16(2.1%)例发生转移,5例经细胞学检查证实。6例患者治疗前死亡,10例接受化疗和随后的手术及放疗。其中4例患者接受多西他赛-5氟尿嘧啶-顺铂(TPF)化疗,1年和3年总生存率分别为50%和24%,
At present, there are few reports on the study of SCCHN. The first chemotherapy-induced patients have obvious local lesion response, and the prognosis is better than that of recurrent SCCHN. The author of the January 2008 - July 2012 SCCHN patients were analyzed retrospectively. Survival was calculated using Kaplan-Meier method. As a result, of the 749 patients included, 16 (2.1%) had metastases and 5 had been confirmed by cytology. Six patients died before treatment, and 10 received chemotherapy and subsequent surgery and radiotherapy. Four of these patients received docetaxel-5-fluorouracil-cisplatin (TPF) chemotherapy, with 1-year and 3-year overall survival rates of 50% and 24%, respectively,