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溃疡性结肠炎（ＵＣ）的病因和发病机制尚未完全阐明，已知免疫功能紊乱在ＵＣ发病机制中有重要作用［１－３］，但对发生免疫功能紊乱的基因调控机制以及皮质激素对参与ＵＣ免疫调控基因表达的影响还不了解，由于淋巴细胞凋亡发生异常是导致免疫紊乱和一些疾病发生的重要原因
The etiology and pathogenesis of ulcerative colitis (UC) have not yet been completely elucidated. It is known that immune dysfunction plays an important role in the pathogenesis of UC [1-3]. However, the mechanism of gene regulation for immune dysfunction and the mechanism of corticosteroid participation The effect of UC immunomodulatory gene expression is not well understood, as aberrant lymphocyte apoptosis is an important cause of immune disorders and some diseases