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尽管实体器官移植术后移植物及患者的存活率近年有了显著提高,但是移植受者较之普通人群心血管疾病(CVD)的患病率却在不断增加。很多因素包括高血压、血脂异常、糖尿病等均可导致这一人群CVD患病风险的增加。其中,移植后新发生糖尿病可能是最重要的因素之一,会导致移植物功能下降和患者存活率降低,移植物失功风险增加。2004年更新的移植后新发生糖尿病治疗和管理指南,不仅明确了疾病的定义、诊断和治疗方法,并涵盖了肾、肝及心脏移植后新发生糖尿病的诊治的诊治。
Despite the significant increase in graft and patient survival after solid organ transplantation in recent years, the prevalence of cardiovascular disease (CVD) in transplant recipients is on the rise. A number of factors, including hypertension, dyslipidemia, diabetes, etc., can contribute to the increased risk of CVD in this population. Among them, new-onset diabetes mellitus after transplantation may be one of the most important factors, resulting in decreased graft function and decreased patient survival, and an increased risk of graft failure. The 2004 Guidelines for the Management and Management of Newly Transplanted Post-transplant Diabetes not only define the definition, diagnosis and treatment of diseases, but also cover the diagnosis and treatment of new-onset diabetes mellitus after kidney, liver and heart transplantation.