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目的:探讨血小板输注治疗特发性血小板减少性紫癜的临床效果.方法筛选2009年1月~2014年1月我院收治的特发性血小板减少性紫癜(ITP)患者98例,作为研究对象.输注前后24 h进行全自动血细胞分析仪计数PLT数量并校正CCI,其中PLT5*10^9/L患者62例,采用随机数表法将其分为输注组与未输注组,每组49例,未输注组仅采取激素治疗,输注组在激素治疗基础上进行输注少白细胞同型单采血小板制剂,比较两组患者临床转归及输注治疗有效率.结果未输注组中PLT5*10^9/L患者中发生1例颅内出血收入ICU;输注组以CCI计算公式作为评价标准(CCI 24<4.5*109/L为无效),其中共有34例患者输注无效,无效率为69.39%,但均无各类出血性疾病出现.结论对ITP患者采取血小板输注治疗效果不理想,输注无效率较高,但作为预防性输注对预防出血疾病效果较为显著,因此临床针对血小板输注应根据患者实际情况谨慎选择. “,”Objective To investigate the changes of platelet infusion for the treatment of idiopathic thrombocytopenic purpura clinical effect.Methods ITP98 patients in 2009 January to 2014 January screening in our hospital, as the research object. Before and after infusion of 24 h automatic blood cell analyzer PLT and correction of CCI, including 36 cases of PLT 〈 5 *10^9/L patients, PLT 〉 62 cases of 5 * 10^9/L in patients with random number table method, all patients were divided into infusion group and the non transfusion group, 49 cases in each group, the non transfusion group only taking hormone therapy infusion group, transfusion of leukocyte reduced isotype platelet apheresis formulations based on hormone therapy, compared two groups of patients with clinical outcome and infusion treatment efifciency.Results No infusion group PLT 〈 18 cases of 5*10^9/L patients, 4 patients had hemorrhagic shock and death, 1 cases of intracranial hemorrhage of income ICU PLT 〉 5* 10^9/L patients; infusion group with CCI 24 〈 4.5 * 10^9/L is invalid, the total of 34 cases of patients with transfusion refractoriness, no efficiency is 69.39%, but there were no various hemorrhagic diseases appear.Conclusion Taking the platelet transfusion treatment effect is not ideal for ITP patients, infusion of invalid rate higher, but as a prophylactic infusion is more signiifcant effect in the prevention of diseases for bleeding, therefore clinical platelet transfusion should be careful to choose according to the actual situation of patients.