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目的:探讨老年无功能垂体腺瘤的早期诊断与治疗特点。方法:回顾分析４３例经手术及病理证实的６０岁以上老年无功能垂体腺瘤的临床特点及治疗效果。结果:肿瘤全切除和次全切除２９例,３２例随访７~１２７个月,生存良好２８例,肿瘤消失２３例,残瘤静止５例,复发４例。结论:老年垂体瘤主要表现为视力障碍(９１%)和垂体功能低下(７０%);经蝶入路显微手术是安全、有效的治疗手段;对残留或复发病人可辅以放疗,但需注意垂体功能低下的并发症。
Objective: To investigate the characteristics of early diagnosis and treatment of elderly non-functional pituitary adenomas. Methods: The clinical features and therapeutic effects of 43 cases of non-functioning pituitary adenoma confirmed by surgery and pathology were retrospectively analyzed. RESULTS: Twenty-nine patients underwent total resection and subtotal resection. 32 patients were followed up for 7 to 127 months. 28 patients survived well, 23 tumors disappeared, 5 remnants remained stationary, and 4 relapsed. Conclusion: Older pituitary adenomas are mainly characterized by visual impairment (91%) and hypopituitarism (70%); transsphenoidal microsurgery is a safe and effective treatment; residual or relapsed patients may be supplemented by radiotherapy, but Pay attention to pituitary complications.