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目的：寻找能兼顾防治高脂血症、动脉粥样硬化和脂肪肝的有效药物。方法：观察普伐他丁、维生素Ｅ、卡托普利对家兔高脂血症、动脉粥样硬化和脂肪肝形成的影响。结果：普伐他丁可显著降低血脂和改善动脉粥样硬化病变，并有抗脂肪肝作用，联用维生素Ｅ可减轻其潜在的肝毒性；卡托普利有一定的抗动脉粥样硬化作用，且不影响血脂和肝脂质代谢。结论：普伐他丁联用维生素Ｅ、卡托普利可安全用于高脂血症、动脉粥样硬化和脂肪肝患者的治疗
Objective: To find effective drugs that can take into account the prevention and treatment of hyperlipidemia, atherosclerosis and fatty liver. Methods: To observe the effects of pravastatin, vitamin E and captopril on hyperlipemia, atherosclerosis and fatty liver in rabbits. Results: Pravastatin can significantly reduce blood lipids and improve atherosclerotic lesions, and the role of anti-fatty liver, combined with vitamin E can reduce its potential hepatotoxicity; captopril has some anti-atherosclerotic effect , And does not affect lipid and liver lipid metabolism. Conclusions: Combination of pravastatin with vitamin E and captopril can be safely used in the treatment of patients with hyperlipidemia, atherosclerosis and fatty liver