先证者 (Ⅲ_9),男,46岁,河北省清苑县人。眼部检查:视力0.08(双),色觉正常,双眼角膜中央呈灰白色混浊,混浊间有大小不等、边界清楚的白色结节状环形混浊点,达角膜浅层及实质层。角膜表面光滑,无新生血管,荧光素染色(-)。由角膜周边透明区 The proband (Ⅲ_9), male, 46 years old, Qingyuan County, Hebei Province. Eye examination: visual acuity 0.08 (double), normal color vision, both eyes central corneal gray turbidity, turbidity between the size, the clear white nodular ring turbidity point, up to the corneal superficial and parenchymal. Corneal surface smooth, no neovascularization, fluorescein staining (-). By the corneal transparent zone around