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总结我科自１９５６～１９９０年内共收治的１０７例口腔颌面部恶性黑色素瘤病例治疗经验。本组资料显示，该肿瘤好发年龄组为４０～５９岁组占５２．３％，原发于粘膜者占９３．５％，皮肤仅占６．５％。好发部位依次是腭部４３％，牙龈３５％，而唇、舌部少见。除１０例失访外（作死亡计算）余下９７例患者分别随访３～１２年，随访率为９２．４％，全组３，５年生存率分别是４５．８％，３１．８％。死亡病例７９例，其中死于局部复发３２．８％，远处转移４４．３％，淋巴转移６．３％，其它死因占１６．５％。比较不同治疗方法的疗效表明：①手术切除原发灶组３，５年生存率均为０％。冷冻治疗原发灶组则为３７．５％，３１．２％。后者优于前者，有统计学差别。②选择性颈清２５例，３，５年生存率为５２．６％，３０．０％，治疗性颈清３７例，其３，５年生存率为４０．６％，１９．２％，无统计学差异，但提示前者组中患者预后稍好。本组资料颈清病检中淋巴结阳性率高达７９．０％。ｃＮ＿０有５３％转移阳性率。作者建议做选择性颈清扫术是必须的。③１０７例中手术、冷冻及综合治疗三种治疗方法的比较，显示以综合治疗法为最好。因此，作者以为恶性黑色素瘤应该综合治疗，颈清也是必须的。
To sum up our department from 1956 to 1990 were treated 107 cases of oral and maxillofacial malignant melanoma cases of treatment experience. The group data show that the incidence of malignant tumors of the age group of 40 to 59 accounted for 52.3% of the group, the primary mucosa accounted for 93.5%, the skin accounted for only 6.5%. Good hair parts followed by 43% of the palate, gums 35%, while the lips, tongue rare. The remaining 97 patients were followed up for 3 to 12 years except for 10 lost patients. The follow-up rate was 92.4%. The 3- and 5-year overall survival rates were 45.8% and 31.8% respectively. 79 cases died, of which 32.8% died of local recurrence, distant metastasis 44.3%, lymphoid metastasis 6.3%, other causes accounted for 16.5%. The curative effects of different treatments showed that: (1) Survival rates of 3 and 5 years in primary resection group were 0%. Frozen primary treatment group was 37.5%, 31.2%. The latter is better than the former, with statistical differences. ②Selective neck dissection in 25 cases, 3, 5-year survival rate was 52.6%, 30.0%, 37 cases of therapeutic neck clearance, the 3, 5-year survival rate was 40.6%, 19.2% No statistical difference, but suggesting that the former group of patients slightly better prognosis. This group of cervical lymph node disease positive rate of 79.0%. cN_0 53% positive rate of transfer. The authors suggest that selective neck dissection is a must. ③ 107 cases of surgery, freezing and comprehensive treatment of three kinds of treatment comparison, show that the best combination therapy. Therefore, the authors believe that malignant melanoma should be combined treatment, neck clearance is also necessary.