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报道9例肠道小细胞癌(ISCC)。通过病理组织形态、组化及免疫组化,并结合临床表现对此癌进行回顾性研究。结果表明:ISCC较少见,占肠道上皮性恶性肿瘤的1.2％;组织学形态可分为四型,即雀麦细胞型;淋巴细胞样型,中间细胞型以及复合性细胞型;免疫组化染色其神经内分泌标记阳性率较高,对NSE和CgA显示一定敏感性和特异性反应;ISCC有较明显侵犯血管倾向(87.5％),淋巴结(62.5％)和肝(66.7％)转移率较高,预后不良,这些临床与病理特征和肺小细胞癌相似。采用综合治疗可望提高此癌患者的生存期。
Nine cases of intestinal small cell carcinoma (ISCC) were reported. The retrospective study of this cancer was performed by histopathological histology, histochemistry and immunohistochemistry, combined with clinical manifestations. The results showed that: ISCC is rare, accounting for 1.2% of intestinal epithelial malignant tumors; histological morphology can be divided into four types, namely, brome cell type; lymphocyte type, intermediate cell type and complex cell type; immune group The positive rate of neuroendocrine markers was higher in metaplastic staining, showing a certain sensitivity and specific response to NSE and CgA; ISCC had a more obvious tendency to invade blood vessels (87.5%), lymph node (62.5%) and liver (66.7%) were more metastatic rate High, poor prognosis, these clinical and pathological features and lung small cell carcinoma are similar. Comprehensive treatment is expected to improve the survival of this cancer patient.