论文部分内容阅读
目的:探讨肝炎性肌纤维母细胞瘤(HIMT)的诊断和治疗经验。方法:回顾性分析2000年1月至2007年8月收治的12例HIMT患者的临床、病理学和影像学资料。结果:12例患者中男7例,女5例,中位年龄27.5岁(19～70岁)。患者多无明显临床症状,血清AFP检查正常,肝功能均为Child A级;CT扫描有一定的特征性表现;3例通过超声引导下穿刺活检确诊,其余9例术前未获明确诊断。12例患者均行手术切除后病理检查确诊,肿瘤均为单发,直径2～12 cm,均无明显包膜,无围术期死亡。9例术后随访10个月～6年,均未见肿瘤复发或转移。结论:HIMT的诊断依赖于临床、实验室和影像学检查,术前很难明确诊断。鉴于HIMT是一种低度恶性肿瘤,建议早期手术治疗。
Objective: To investigate the diagnosis and treatment of hepatitis myofibroblastoma (HIMT). Methods: The clinical, pathological and imaging data of 12 patients with HIMT admitted from January 2000 to August 2007 were retrospectively analyzed. Results: Among the 12 patients, there were 7 males and 5 females with a median age of 27.5 years (19-70 years). There were no obvious clinical symptoms, serum AFP was normal, and liver function was Child A grade. CT scan had some characteristic features. Three cases were diagnosed by ultrasound guided biopsy, and the other 9 cases were not diagnosed preoperatively. All of the 12 patients were diagnosed by pathology after the surgical resection. The tumors were all single, with a diameter of 2 ~ 12 cm. There was no obvious capsule and no perioperative death. Nine patients were followed up for 10 months to 6 years, no tumor recurrence or metastasis. Conclusions: The diagnosis of HIMT depends on clinical, laboratory and imaging studies and is difficult to diagnose preoperatively. Given that HIMT is a low-grade malignancy, early surgical treatment is recommended.