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卵巢癌是常见的妇科恶性肿瘤之一,由于缺乏早期诊断的手段,很多患者在诊断时已达晚期.而晚期病人由于手术难以彻底及化疗药物的耐受性,患者常于术后1～2年中复发.虽然二线药物泰素对复发患者有30%的疗效,但仍不能解决药物的耐受性问题.而白细胞介素2作为免疫调节剂不受药物的耐受性的限制,可望对复发及转移的晚期卵巢癌有一定的治疗作用.本研究应用重组白细胞介素2及化疗联合应用治疗卵巢癌的复发及转移灶,探讨重组白细胞介素2治疗实体肿瘤的作用效果,为有效冶疗复发和转移的卵巢癌提供一种方法.
Ovarian cancer is one of the common gynecologic malignancies, many of whom have reached the advanced stage of diagnosis due to the lack of early diagnosis, while patients with advanced disease are difficult to complete and chemotherapeutic drugs due to surgery, patients often in 1 to 2 Year recurrence.Although the second-line drug taxol in patients with recurrent 30% of the efficacy, but still can not solve the problem of drug tolerance, while the interleukin 2 as an immunomodulator is not tolerated by drugs, is expected to On the recurrence and metastasis of advanced ovarian cancer have a certain therapeutic effect.In this study, the combination of recombinant interleukin 2 and chemotherapy in the treatment of ovarian cancer recurrence and metastasis to explore the effect of recombinant interleukin 2 in the treatment of solid tumors, effective Treatment of recurrent and metastatic ovarian cancer provides a method.