目的 :评价改良Siepser法用于瞳孔成形的效果。方法 :对 5例 5眼瞳孔变形患者施行无缝线角膜切口瞳孔成形术 ,手术前后分别检测视力、瞳孔形状、角膜内皮细胞密度和角膜曲率 ,术后随访 3～ 13个月。结果 :术后视力有不同程度提高 ,畏光和眩目等症状明显减轻或消除 ,角膜内皮细胞丧失率约 3 % ,角膜散光减轻。结论 :改良Siepser法是一种安全有效的瞳孔成形术 Objective: To evaluate the effect of modified Siepser method on pupil formation. Methods: Five patients (5 eyes) with pupil deformity underwent corneal incision. The visual acuity, pupil shape, corneal endothelial cell density and corneal curvature were measured before and after operation. The patients were followed up for 3 to 13 months. Results: Postoperative visual acuity improved to varying degrees, photophobia and dizziness and other symptoms significantly reduced or eliminated, corneal endothelial cell loss rate of about 3%, corneal astigmatism reduced. Conclusion: Modified Siepser method is a safe and effective pupilloplasty