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多发性硬化(MS)是一种中枢神经系统的脱髓鞘疾病,其发病机制与病毒感染和自身免疫有关。本文测定2 4例MS患者急性发作期血清和脑脊液(CSF)中TNF -α和IL -10含量和比值,探讨促炎性细胞因子和抑炎性细胞因子在该病的发生过程中的作用。1 资料和方法1·1 一般资料 MS组2 4例,
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system whose pathogenesis is related to viral infection and autoimmunity. In this paper, the content and ratio of TNF-α and IL-10 in serum and cerebrospinal fluid (CSF) of 24 patients with acute exacerbation of MS were measured to explore the role of proinflammatory cytokines and anti-inflammatory cytokines in the pathogenesis of this disease. 1 Materials and Methods 1.1 General Information MS group 24 cases,