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张××,女,出生3个月,因鼻塞、喉头痰鸣一个月,以上呼吸道感染收入住院。患者为同卵双胎双女婴中的小婴,同卵双胎中另一健康,入院时无发热及出血症状。体检:轻度贫血外貌,肝肋下4cm,剑突上3.5cm,脾未触及,实验室检查:Hb 90.5g/L,WBC 177.5×10~9/L,BPC 50×10~9/L,分类:早幼粒82％,中幼粒2％,晚幼粒2％,中性分叶核10％,淋。巴4％;骨髓象:骨髓增生极度活跃,以颗粒异常的早幼粒细胞增生为主,早幼粒占79％,中、晚幼粒以下占15％,幼红4％,淋巴2％,部分胞浆可见Aner’s小体,POX++～++++,非特异性脂酶阳性,氟化钠不抑制,诊断为急性早幼粒细胞白血病(ANLL-M_3)。
Zhang × ×, female, born 3 months, due to nasal congestion, throat phlegm for a month, more than the income of respiratory infections in hospital. The patient was an identical baby with two identical twins and another with identical twins, with no fever and bleeding at admission. Physical examination: mild anemic appearance, liver ribs 4cm, xiphoid on the 3.5cm, spleen not touched, laboratory tests: Hb 90.5g / L, WBC 177.5 × 10 ~ 9 / L, BPC 50 × 10 ~ 9 / L, Category: Progeny seed 82%, 2% in juvenile grains, late juvenile 2%, neutral leaf core 10%, leaching. Pakistan 4%; bone marrow like: bone marrow hyperplasia is extremely active, with abnormal promyelocytic granulocyte-based, promyelocytic 79%, 15% below the young, young 4%, lymphatic 2% Some of the cytoplasm showed Aner’s body, POX ++ ~ ++++, non-specific lipase positive, sodium fluoride did not inhibit the diagnosis of acute promyelocytic leukemia (ANLL-M_3).