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目的体外观察人参与林蛙油配伍的保健食品能否诱发鼠伤寒沙门氏菌组氨酸营养缺陷型突变株的回复突变。方法 Ames试验用TA97、TA98、TA100、TA102菌株并分加与不加肝微粒体酶活化系统(+/-S9)试验。结果人参与林蛙油配伍的保健食品对4个菌株各剂量组的回复菌落数都未超过自然回复菌落数,Ames试验结果为阴性。结论在5000-8μg/皿剂量下未见人参与林蛙油配伍的保健食品致突变性。
Objective To observe whether the human health food with Rana chensinensis oil can induce the reversion of histidine auxotrophic mutant of Salmonella typhimurium in vitro. Methods Ames test TA97, TA98, TA100, TA102 strains with and without liver microsomal enzyme activation system (+/- S9) test. Results The results showed that the number of colonies recovered from the four health-care foods did not exceed the number of naturally-recovered colonies. The Ames test result was negative. Conclusion No mutagenicity was observed in health food supplemented with Radix Angelicae Sinensis at 5000-8μg / dish.