Ghrelin是近年来发现的一种促进生长激素分泌的多肽,是生长激素促分泌物受体的内源性配体。研究发现,ghrelin除了具有增加摄食及调节能量代谢的作用外,还具有降低血压、对抗炎症反应、保护血管内皮细胞等多种生物学效应,提示其在心血管疾病尤其是在动脉粥样硬化方面具有潜在的治疗效应。 Ghrelin is a polypeptide found in recent years that promotes the secretion of growth hormone and is an endogenous ligand for the growth hormone secretagogue. Studies have found that, in addition to ghrelin to increase food intake and regulate energy metabolism, but also has lower blood pressure, anti-inflammatory response, protection of vascular endothelial cells and other biological effects, suggesting that it has cardiovascular disease, especially in atherosclerosis Potential therapeutic effect.