家兔18只喂以高胆固醇食物,1～20周内以不同的间隔期间主动脉内灌注戊二醛处死。另用4只家兔喂以普通食物作对照。用伊文思蓝染来显示动脉壁的通透性变化。在早期斑块形成前,扫摸电镜下见内皮细胞收缩、隙口开大和内皮细胞肿 Eighteen rabbits were fed with high cholesterol food, and glutaraldehyde was aortic instilled at different intervals during 1 ~ 20 weeks. Another four rabbits fed normal food as a control. Evans blue staining was used to show changes in arterial wall permeability. Before the early plaque formation, under the scanning electron microscope, endothelial cell contraction, gap opening and endothelial cell swelling