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虽然他汀类药物降低心血管疾病风险的作用十分明确,但对其应用风险的了解较少.以前有关他汀类药物不良反应的研究往往仅集中在少数不良反应而非整体的不良反应谱,如既往的荟萃分析仅对转氨酶升高或肿瘤的发生率以及横纹肌溶解进行了评估.汇总临床试验数据是判断他汀类药物治疗
Although the role of statins in reducing the risk of cardiovascular disease is well defined, less is known about the risks of statin use.Studies on previous adverse drug reactions often focus on a small number of adverse reactions rather than the overall adverse response spectrum, as in the past Meta-analysis was only evaluated for elevated transaminases or tumor incidence and rhabdomyolysis.Collected clinical trial data to determine statin therapy