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目的了解广州市新源野生动物市场从业人员严重急性呼吸综合征(SARS)抗体产生情况及其暴露果子狸的关系。方法对野生动物市场从业人员中的志愿者进行SARS病毒血清抗体监测,对监测结果结合果子狸在市场的存在情况进行分析。结果2003年5和12月、2004年1和7月、2005年6月,共5次分别对328、238、135、139和53名市场从业人员开展调查,SARS病毒IgG抗体检出率依次为25．61%、13．03%、12．59%、5．04%和9．43%,没有检测到SARS病毒IgM抗体。在接受2次以上随访调查的129人中,97人的血清抗体一直为阴性,18人一直为阳性；有13人从阳性转为阴性,有1人从阴性转为阳性。在清除果子狸后进入市场的工作人员,SARS病毒IgG抗体检测全部阴性。结论广州市新源野生动物市场从业人员SARS病毒抗体检出率和市场内果子狸的存在情况密切相关。
Objective To understand the antibody production of severe acute respiratory syndrome (SARS) among practitioners in Guangzhou Xinyuan Wild Animal Market and the relationship between exposure of civets and the results. Methods The SARS virus serum antibody was monitored in the volunteers in the wild animal market and the monitoring results were combined with the presence of civets in the market. Results In May, December and December 2003, in January and July 2004 and June 2005, the survey conducted a total of 328,238,135,139 and 53 market practitioners respectively. The detection rate of IgG antibodies to SARS virus was 25.61%, 13.03%, 12.59%, 5.04% and 9.43% respectively. No SARS virus IgM antibody was detected. Of the 129 people who were surveyed for more than two visits, 97 had a negative serum antibody and 18 had been positive; 13 had changed from positive to negative, and one changed from negative to positive. After clearing the civet cats entered the market staff, SARS virus IgG antibody test all negative. Conclusions The detection rate of SARS virus antibody among the employees of Xinyuan wild animal market in Guangzhou is closely related to the existence of civet cats in the market.