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目的:分析老年胃癌患者预后因素及不同年龄组老年胃癌患者的临床病理特点及其预后差异。方法:回顾性分析天津医科大学附属肿瘤医院1996年7月至2006年7月间行胃癌根治术的435例老年胃癌患者(年龄≥65岁)的临床病理特点及其预后影响因素结果:单因素分析结果显示年龄分组、肿瘤部位、手术方式、联合切除、病理类型、肿瘤大小、T分期、N分期、临床分期是影响老年胃癌患者预后的因素。多因素分析结果显示年龄分组、联合切除、T分期、N分期是影响老年胃癌患者预后的独立因素对比分析不同年龄组老年胃癌患者的临床病理特点,结果显示肿瘤部位、手术方式、肿瘤大小、术后化疗在不同年龄组老年胃癌患者间比较差异有统计学意义(P<0.05)。对不同年龄组老年胃癌患者的预后进行分析结果显示不同年龄组老年胃癌患者的预后影响因素不同结论:不同年龄组老年胃癌患者在临床病理特点、预后影响因素方面存在差异,将老年胃癌患者分为不同年龄组进行研究具有重要意义,可以更好的指导治疗和判断预后。
OBJECTIVE: To analyze the prognostic factors of elderly patients with gastric cancer and the clinicopathological characteristics and prognosis of elderly patients with gastric cancer of different age groups. Methods: The clinicopathological features and prognostic factors of 435 elderly patients with gastric cancer who underwent radical gastrectomy between July 1996 and July 2006 at the Tumor Hospital Affiliated to Tianjin Medical University were retrospectively analyzed. Results Single-factor The results showed that the age group, tumor location, operation method, combined resection, pathological type, tumor size, T stage, N stage and clinical stage were the factors affecting the prognosis of elderly patients with gastric cancer. Multivariate analysis showed that age group, combined resection, T stage and N stage were independent factors influencing the prognosis of elderly patients with gastric cancer. The clinicopathological characteristics of elderly patients with gastric cancer were analyzed by comparative analysis. The results showed that the tumor location, operation method, tumor size, After chemotherapy in different age groups of elderly patients with gastric cancer was significantly different (P <0.05). The prognosis of elderly patients with gastric cancer in different age groups showed that prognostic factors of elderly patients with gastric cancer of different age groups were different Conclusion: There are differences in the clinicopathological features and prognostic factors between elderly patients with gastric cancer in different age groups, Research of different age groups is of great significance, can better guide the treatment and prognosis.