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目的探讨嗅裂疾病的诊断和治疗问题。方法回顾性分析2003年12月至2006年5月经治的8例嗅裂疾病患者的资料。通过复习国内外文献,对嗅裂解剖、嗅裂疾病的诊断和治疗问题展开讨论。结果 8例嗅裂疾病患者的病理诊断分别为高分化腺癌、低分化鳞状细胞癌、内翻性乳头状瘤、神经胶质细胞瘤伴脑脊液鼻漏、上鼻甲脓囊肿、血管纤维骨瘤、神经纤维瘤和血管瘤。临床表现主要为一侧鼻塞和鼻出血。所有患者均接受了鼻内镜手术,对2例恶性肿瘤患者术后给予放疗。结论原发于嗅裂的疾病并不少见,只是以往对嗅裂疾病认识不足。为了防止误诊,首先应加强对嗅裂这一解剖部位的认识;其次要重视嗅裂疾病的特殊性,特别是巨大的嗅裂肿瘤,手术前仅凭 CT 扫描不能准确判定肿瘤的原发部位,只有在手术中,内镜下才能看到肿瘤的蒂部。在治疗方面,应首选内镜下手术,对于嗅裂的恶性肿瘤,手术后应当给予放疗。
Objective To investigate the diagnosis and treatment of snoring and cracking diseases. Methods The data of 8 patients with olfactory dehiscence disease treated from December 2003 to May 2006 were retrospectively analyzed. Through reviewing the literature both at home and abroad, we discuss the diagnosis and treatment of olfactory cleft dissection and olfactory fissure disease. Results The pathological diagnosis of 8 patients with olfactory dehiscence was as follows: high differentiated adenocarcinoma, poorly differentiated squamous cell carcinoma, inverted papilloma, glioma with cerebrospinal fluid rhinorrhea, supranuclear turbidus pus cyst, , Neurofibromatosis and hemangiomas. The main clinical manifestations of nasal congestion and nose bleeding. All patients underwent endoscopic sinus surgery and radiotherapy was given to 2 patients with malignant tumors after surgery. Conclusion The origin of the disease in the olfactory fissure is not uncommon, but in the past lack of understanding of olfactory cleft disease. In order to prevent misdiagnosis, we should first strengthen the understanding of the anatomical part of olfactory fissure. Secondly, we must pay attention to the particularity of olfactory fissure disease, especially huge olfactory fissure tumors. CT scan can not accurately determine the primary tumor site before surgery, Only in surgery, endoscopic tumor to see the pedicle. In the treatment, endoscopic surgery should be the first choice, for olfactory rupture of malignant tumors, radiotherapy should be given after surgery.