论文部分内容阅读
目的:了解我院ICU临床分离病原菌种类及对常用抗菌药物的耐药状况。方法:收集2014年1月8日至2015年1月7日ICU临床分离的283株病原菌,并对分析其药敏结果。结果:临床分离的常见致病菌有G-菌(革兰阴性菌)、真菌、G+菌(革兰阳性菌)。其中G-菌主要有肺炎克雷伯菌、大肠埃希菌、铜绿假单胞菌,G+菌主要有凝固酶阴性葡萄球菌、金黄色葡萄球菌。G+菌对利奈唑胺及万古霉素的敏感率为100%,对其他抗菌药物耐药率较高;G-菌中的肺炎克雷伯菌及大肠埃希菌对亚胺培南敏感率为100%,其他细菌耐药程度各不一样。真菌感染超过G+球菌,对各类抗真菌药的耐药率均不高。结论:需高度重视ICU细菌耐药状况,真菌感染比例较高,且耐药率较低。应针对细菌分布及特点,科学合理地使用抗菌药物,减少细菌感染的同时减少耐药细菌的产生和蔓延。
Objective: To understand the clinical isolates of ICU in our hospital and their resistance to commonly used antibiotics. Methods: 283 strains of pathogens isolated from the ICU from January 8, 2014 to January 7, 2015 were collected and their susceptibility results were analyzed. Results: The common clinical isolates were G-bacteria (Gram-negative bacteria), fungi and G + bacteria (Gram-positive bacteria). G- bacteria which mainly Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, G + bacteria are coagulase-negative Staphylococcus aureus, Staphylococcus aureus. The sensitivity of G + to linezolid and vancomycin was 100%, and the rate of resistance to other antibacterials was high. The sensitivity of Klebsiella pneumoniae and Escherichia coli to imipenem in G-bacteria was 100%, the degree of resistance of other bacteria are different. Fungal infections over G + cocci, resistance to various antifungal agents are not high. Conclusion: It is necessary to attach great importance to the drug resistance status of ICU bacteria. The fungal infection rate is high and the drug resistance rate is low. Should be based on the distribution and characteristics of bacteria, scientific and rational use of antibacterial drugs to reduce bacterial infections while reducing the generation and spread of drug-resistant bacteria.