创伤、感染或失血的病人,凝血和纤溶系统的活性均会发生显著的变化。本组实验是对出血性休克的犬,在达到不可逆性休克时再静脉注射大肠杆菌内毒素,除观察常规凝血纤溶检查项目外,尚利用显色肽基质S—2238和S—2251测定休克前、休克达到不可逆后以及注射内毒素后,血液凝血纤溶系统活性的变化。 Patients with trauma, infection, or blood loss experience significant changes in coagulation and fibrinolytic activity. This group of experiments on dogs with hemorrhagic shock, intravenous injection of E. coli endotoxin in the irreversible shock, in addition to the observation of routine coagulation and fibrinolysis items, but also the use of chromogenic peptide matrix S-2238 and S-2251 determination of shock Before and after shock reached irreversible and after injection of endotoxin, blood coagulation fibrinolysis system activity changes.