钙通道阻滞剂(CCB)是临床上治疗高血压的常用药物之一,迄今已使用近30年。根据其化学结构和药理作用可分为二氢吡啶(DHP)与非二氢吡啶类。近年来国内、外大型临床试验及高血压防治指南均建议,合理选择长效控释(或缓释)剂型的二氢吡啶类CCB能产生相对平稳和持久的降压效果,并可 Calcium channel blocker (CCB) is one of the commonly used drugs for the clinical treatment of hypertension, which has been used for nearly 30 years. According to its chemical structure and pharmacological effects can be divided into dihydropyridine (DHP) and non-dihydropyridines. In recent years, domestic and foreign large-scale clinical trials and guidelines for the prevention and treatment of hypertension have suggested that a reasonable choice of long-acting controlled release (or sustained release) dihydropyridine CCB can produce a relatively stable and sustained antihypertensive effect, and