铅中毒在蓄电池生产行业及有色金属冶炼行业较为常见,目前的研究工作已经表明,铅主要是影响卟啉代谢,引起周围神经系统功能障碍及肾损伤.脂质过氧化理论是近代膜毒理学的重要观点之一,而且脂质过氧化作用与许多疾病及中毒的发生有着密切的关系。因此,本文从脂质过氧化理论出发,采用动物实验及人群调查相结合的方法,研究了铅致脂质过氧化作用,为研究铅中毒机理提供理论依据. Lead poisoning in the battery manufacturing industry and non-ferrous metal smelting industry is more common, the current research work has shown that lead is mainly affect the metabolism of porphyrin, causing peripheral nervous system dysfunction and renal damage. Lipid peroxidation theory is modern membrane toxicology One of the important points, and lipid peroxidation and many diseases and the occurrence of poisoning are closely related. Therefore, based on the theory of lipid peroxidation, this paper studied the lead-induced lipid peroxidation using animal experiments and population surveys to provide a theoretical basis for the study of lead poisoning mechanism.