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目的:评价保留生育功能的宫颈根治性切除术治疗早期宫颈癌的可行性与临床效果。方法:回顾性分析2002年12月至2008年9月,行保留生育功能的宫颈根治性切除术的9例早期宫颈癌患者的临床资料。结果:9例要求保留生育功能的早期宫颈癌患者成功实施了盆腔淋巴结清扫+宫颈根治性切除术,患者平均年龄为30岁(25~38岁)。临床分期按国际妇产科联盟(FIGO)标准,Ia期5例,Ib1期4例;病理类型均为鳞癌。8例采用Dargent术式,1例采用Ungar术式。平均随诊24个月均无瘤生存,全部患者术后均恢复正常月经。1例患者术后行辅助妊娠成功但妊娠3个月时流产。结论:对早期宫颈癌患者施行保留生育功能的子宫颈根治性切除术的治疗是可行的。
OBJECTIVE: To evaluate the feasibility and clinical efficacy of radical cervical resection for fertility preservation in early stage cervical cancer. METHODS: The clinical data of 9 patients with early cervical cancer who underwent radical resection of fertility preservation from December 2002 to September 2008 were retrospectively analyzed. RESULTS: Nine patients with early-stage cervical cancer who required retention of reproductive function were successfully treated with pelvic lymph node dissection and radical cervixectomy. The average age of the patients was 30 years old (25-38 years old). The clinical stage was according to the International Federation of Obstetrics and Gynecology (FIGO) criteria. There were 5 cases in stage Ia and 4 cases in stage Ib1. The pathological types were squamous cell carcinoma. Eight patients were treated with the Dargen procedure and one patient was treated with the Ungar procedure. The average follow-up time was 24 months without tumor survival, all patients returned to normal menstruation after surgery. One patient had a successful assisted pregnancy but had a miscarriage at 3 months of pregnancy. Conclusion: It is feasible to treat cervical cancer patients who have preserved reproductive function in early stage of cervical cancer.