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目的:研究来曲唑治疗排卵障碍性不孕的效果以及对血清激素水平的影响。方法:在我院于2015年2月-2016年8月间收治的排卵障碍性不孕患者中随机选出130例为本次研究的观察对象,将患者以随机方式分入到观察组和对照组中,观察组患者采用来曲唑治疗,对照组患者采用克罗米芬治疗,对比分析两组患者的治疗效果差异。结果:观察组患者的治疗总有效率显著高于对照组(96.92%vs 87.69%,P<0.05)。且观察组患者治疗后的LH水平和T水平均低于对照组(P<0.05)。观察组患者的卵泡发育率明显高于对照组,且卵泡未破裂黄素化发生率低于对照组(P<.05)。结论:来曲唑用于排卵障碍性不孕治疗中效果确切,有助于促进排卵,改善激素水平,值得在临床治疗中推广应用。
Objective: To study the effect of letrozole in the treatment of ovulatory dysplasia and its effect on serum hormone levels. Methods: A total of 130 patients with ovulation disorder infertility who were treated in our hospital from February 2015 to August 2016 were randomly selected as the observation subjects. The patients were randomly divided into observation group and control group Group, the observation group patients with letrozole treatment, the control group patients with clomiphene citrate treatment, comparative analysis of two groups of patients with different treatment effects. Results: The total effective rate in observation group was significantly higher than that in control group (96.92% vs 87.69%, P <0.05). The LH and T levels in the observation group were lower than those in the control group (P <0.05). The rate of follicular development in the observation group was significantly higher than that in the control group, and the incidence of unruptured luteinization was lower in the observation group than in the control group (P <.05). Conclusion: Letrozole is effective in ovulation disorder infertility treatment, which can promote ovulation and improve hormone levels. It is worth to be popularized and applied in clinical treatment.